Posts Tagged: "autoimmune disorders"

Pfizer Focuses Recent Patent Activity on Antibacterial Agents

Patent applications recently published by the U.S. Patent and Trademark Office show that Pfizer’s recent development goals have focused on a broad spectrum of diseases and disorders… Treatments for a number of bacterial infections which can develop in hospital settings was another field of innovation reflected both in Pfizer’s patent applications as well as the patents recently assigned to the company. A couple of recently issued patents protect treatments against gram-negative bacteria by inhibiting a catalyst enzyme necessary for bacterial reproduction.

Patent Granted on Long-Acting Drug for Multiple Sclerosis

The conjugates covered by this patent could enable less frequent and better tolerated dosing of one of the most widely used treatments worldwide for relapsing-remitting multiple sclerosis, interferon-beta-1b. The invention described in the European Patent relates to methods for the preparation of conjugates of poly(ethylene glycol), and derivatives thereof, with interferon-beta-1b. Compared to the corresponding unconjugated bioactive components, the conjugates of the invention have increased stability (i.e., longer shelf life and longer half-lives in vivo). In addition, compared to conjugates of the same bioactive component prepared with polymer chains that are attached randomly to solvent-accessible sites along the polypeptide chains, the conjugates of the invention have increased receptor-binding activity and increased potency.