Posts Tagged: "carcinoma"

The University of Texas: Biomedical Innovation Focus

Many of the University of Texas’s medical developments involve the use of synthetic materials to aid in treating patients. One patent application would protect a scaffold for tissue engineering that biodegrades and delivers treatment over time. Another application describes a system of using nanoparticles to stimulate hyperthermia to treat tumors. A third application discusses an improved bioadhesive for sealing tissues together. Other notable patent application filings pertain to improved systems of diagnosing and treating diseases that usually cause a poor prognosis in patients. One patent application deals with a system of analyzing gene expressions to determine a patient’s susceptibility to renal cell carcinoma. A final application we feature provides for a more effective course of treatment for most gastrointestinal tract infections.

Steve Brachmann

September 17, 2013

Patent Granted on Long-Acting Drug for Multiple Sclerosis

The conjugates covered by this patent could enable less frequent and better tolerated dosing of one of the most widely used treatments worldwide for relapsing-remitting multiple sclerosis, interferon-beta-1b. The invention described in the European Patent relates to methods for the preparation of conjugates of poly(ethylene glycol), and derivatives thereof, with interferon-beta-1b. Compared to the corresponding unconjugated bioactive components, the conjugates of the invention have increased stability (i.e., longer shelf life and longer half-lives in vivo). In addition, compared to conjugates of the same bioactive component prepared with polymer chains that are attached randomly to solvent-accessible sites along the polypeptide chains, the conjugates of the invention have increased receptor-binding activity and increased potency.

Gene Quinn

June 11, 2012