Posts Tagged: "gene editing tools"

British approval of embryonic gene editing research brings CRISPR-Cas9 into focus

England isn’t the only part of the world where embryonic gene editing research has been finding a foothold. In early 2015, researchers out of China published a paper reporting experiments in using CRISPR-Cas9 to edit a specific gene in an embryo’s genetic code responsible for a potentially life-threatening blood disorder. The research team found serious obstacles that need to be addressed before CRISPR-Cas9 can be used to edit genetic code in an embryo on a wide scale; these issues include low retention of genetic material and unintended mutations when a Cas9 enzyme misses its target.

VRC01 and broadly neutralizing antibodies are increasing options for HIV/AIDS treatments

Proteins like VRC01 are referred to as broadly neutralizing antibodies (bNAbs), a type of broad spectrum antibody which is effective in treating against infections of viruses with high mutation rates, such as HIV as well as influenza. It’s thought that VRC01 and other bNAbs useful in treating HIV-infected patients is capable of identifying the envelope spike of a single HIV viral agent to inhibit or neutralize its effects… Gene editing tools may also be part of the solution that rids HIV/AIDS from the human race for good. The discovery of clustered regularly-interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) has given scientists hope that they’ll be able to efficiently edit genomes with a high degree of precision and flexibility.