Posts Tagged: "University of South Florida"

On Tuesday, March 21st, a pre-trial hearing will take place in a case involving patent infringement claims targeting the sale of mice having mutated genes which make them useful for research into Alzheimer’s disease… The original complaint filed in University of South Florida Board of Trustees v. The Jackson Laboratory, which is in the U.S. District Court for the Middle District of Florida (M.D. Fla.), asserts a single patent: U.S. Patent No. 5898094, entitled Transgenic Mice Expressing APPK670N, M671L and a Mutant Presenilin Transgenes. Issued in April 1999, it protects a transgenic mouse with enhanced Alzheimer’s disease-related amyloid accumulation in its brain produced by selecting the offspring of two mice, one expressing the mutant presenilin encoded in its genes and the other expressing the APPK670N, M671L genetic sequence; this results in a mouse that develops accelerated deposition of amyloid beta in a period of weeks rather than nine months.